论文标题
Piezo1和Piezo2功能差异的生物物理序列分析
Biophysical Sequence Analysis of Functional Differences of Piezo1 and Piezo2
论文作者
论文摘要
由于它们的尺寸较大和广泛的机械敏感性相互作用，最近才发现的名为“跨膜蛋白”吸引了很多关注。在这里，我们使用一种新的序列分析方法介绍并讨论了它们的水质谱。我们发现通过常规序列或结构研究无法获得的大规模相似性和差异。这些差异支持了物理学家中流行的进化论 - 关键性猜想。
Because of their large size and widespread mechanosensitive interactions the only recently discovered titled transmembrane proteins have attracted much attention. Here we present and discuss their hydropathic profiles using a new method of sequence analysis. We find large-scale similarities and differences not obtainable by conventional sequence or structural studies. These differences support the evolution-towards-criticality conjecture popular among physicists.
