论文标题
形状张紧耦合在上皮顶点模型中产生列顺序
Shape-tension coupling produces nematic order in an epithelium vertex model
论文作者
论文摘要
我们研究上皮组织力学的顶点模型扩展，包括细胞形状和细胞 - 细胞连接中张力之间的耦合。这种耦合代表了一种活跃的力，它使系统脱离平衡，并导致列秩序的形成，并散布着突出的，长寿的$+1 $缺陷。列秩序中的缺陷耦合到细胞平铺的形状，影响细胞区域和协调。细胞形状，大小和协调之间的这种复杂的相互作用提供了一种可能的机制，通过该机制可以通过局部机械力自发发展长距离极性，而无需诉诸远程化学模式。
We study the vertex model for epithelial tissue mechanics extended to include coupling between the cell shapes and tensions in cell-cell junctions. This coupling represents an active force which drives the system out of equilibrium and leads to the formation of nematic order interspersed with prominent, long-lived $+1$ defects. The defects in the nematic ordering are coupled to the shape of the cell tiling, affecting cell areas and coordinations. This intricate interplay between cell shape, size, and coordination provides a possible mechanism by which tissues could spontaneously develop long-range polarity through local mechanical forces without resorting to long-range chemical patterning.
