论文标题
等离子体和超材料生物传感器:改变病毒检测的游戏改变者
Plasmonic and metamaterial biosensors: A game-changer for virus detection
论文作者
论文摘要
与当前和未来大流行的斗争中最重要的过程之一是对人类病毒治疗的快速诊断和启动。在这些时期,高敏性测试和诊断套件的开发是重要的研究领域。控制次波长体积的光的等离子平台为生物传感应用打开了令人兴奋的前景。它们的显着敏感性和选择性允许对病毒进行非侵入性和快速检测。特别是,可以通过各种方法来实现等离子辅助的病毒检测平台,包括传播表面和局部等离子体共振以及表面增强的拉曼光谱。在这篇综述中,我们讨论了控制等离子生物传感器的基本原理,又讨论了提高传感器性能的前景。我们强调了几种纳米结构方案,以对抗病毒相关的疾病。我们还检查了基于等离子的生物传感的技术局限性和挑战,例如降低复杂生物样品的总成本和处理。最后,我们为改善基于等离子体的方法的机会提供了未来的预期,以增加其对全球健康问题的影响。
One of the most important processes in the fight against current and future pandemics is the rapid diagnosis and initiation of treatment of viruses in humans. In these times, the development of high-sensitivity tests and diagnostic kits is an important research area. Plasmonic platforms, which control light in subwavelength volumes, have opened up exciting prospects for biosensing applications. Their significant sensitivity and selectivity allow for the non-invasive and rapid detection of viruses. In particular, plasmonic-assisted virus detection platforms can be achieved by various approaches, including propagating surface and localized plasmon resonances, as well as surface-enhanced Raman spectroscopy. In this review, we discuss both the fundamental principles governing a plasmonic biosensor and prospects for achieving improved sensor performance. We highlight several nanostructure schemes to combat virus-related diseases. We also examine technological limitations and challenges of plasmonic-based biosensing, such as reducing the overall cost and handling of complex biological samples. Finally, we provide a future prospective for opportunities to improve plasmonic-based approaches to increase their impact on global health issues.