论文标题
小儿创伤后的纵向声音跟踪
Longitudinal Acoustic Speech Tracking Following Pediatric Traumatic Brain Injury
论文作者
论文摘要
小儿创伤性脑损伤(TBI)后对共同结局指标的建议支持仪器测量以及恢复和治疗计划中的感知评估。因此,一组敏感,健壮和非侵入性测量对于评估小儿TBI后随时间的时间的变化至关重要。在本文中,我们研究了十个被诊断为严重TBI的受试者的儿科队列的声音语音模式的变化。在孩子产生可理解的单词后,我们从全年记录的儿童演讲中提取了一系列知名和新颖的声学特征。这些特征是单独和语音子系统,主体内部和整个队列分析的。作为一个小组,年龄较大的儿童表现出高度显着(P <0.01)的音调变化和音素多样性,缩短的停顿长度和稳定的关节率变化。年幼的儿童表现出相似的稳定速率变异性,以及基于共振剂的表达复杂性的增加。对特征设置的相关性分析与年龄和与规范发育数据的比较证实,受伤时的年龄在构建恢复轨迹方面起着重要作用。总体上,几乎所有的语音特征都显着改变(P <0.05),确认需要补充感知评估的声学措施来识别TBI之后的有效治疗目标。
Recommendations for common outcome measures following pediatric traumatic brain injury (TBI) support the integration of instrumental measurements alongside perceptual assessment in recovery and treatment plans. A comprehensive set of sensitive, robust and non-invasive measurements is therefore essential in assessing variations in speech characteristics over time following pediatric TBI. In this article, we study the changes in the acoustic speech patterns of a pediatric cohort of ten subjects diagnosed with severe TBI. We extract a diverse set of both well-known and novel acoustic features from child speech recorded throughout the year after the child produced intelligible words. These features are analyzed individually and by speech subsystem, within-subject and across the cohort. As a group, older children exhibit highly significant (p<0.01) increases in pitch variation and phoneme diversity, shortened pause length, and steadying articulation rate variability. Younger children exhibit similar steadied rate variability alongside an increase in formant-based articulation complexity. Correlation analysis of the feature set with age and comparisons to normative developmental data confirm that age at injury plays a significant role in framing the recovery trajectory. Nearly all speech features significantly change (p<0.05) for the cohort as a whole, confirming that acoustic measures supplementing perceptual assessment are needed to identify efficacious treatment targets for speech therapy following TBI.