论文标题
遗传相似性与遗传祖先作为人类遗传学样本描述符
Genetic similarity versus genetic ancestry groups as sample descriptors in human genetics
论文作者
论文摘要
人类基因组学研究中的一个常见样本描述符是“遗传血统群体”，其术语诸如“欧洲遗传血统”或“东亚遗传祖先”，在出版物中经常使用，以根据其基因型的分析来描述个体群体的遗传学。从这个角度来看，我认为这些术语是不精确的和潜在的误导性的，对于大多数应用，遗传相似性的简单陈述代表了更准确的描述。
A common sample descriptor in human genomics studies is that of 'genetic ancestry group', with terms such as 'European genetic ancestry' or 'East Asian genetic ancestry' frequently used in publications to describe the genetics of groups of individuals based on the analysis of their genotypes. In this Perspective, I argue that these terms are imprecise and potentially misleading and that, for most applications, simple statements of genetic similarity represent a more accurate description.
