论文标题

轴突中的动作电位孤子和波

Action potential solitons and waves in axons

论文作者

Cano, Gaspar, Dilão, Rui

论文摘要

我们表明,轴突内产生的动作电位信号是反应扩散孤子或反应扩散波,反驳了霍奇金和赫x黎假设,即用弹性波机理沿轴突沿轴突传播动作电位。与弹性波相反,反应扩散作用的电势波前和孤子在轴突的碰撞和边界上消灭了弹性波,在弹性波中,幅度加起来并在边界处反射。我们从数值上计算动作电位尖峰和分散关系的速度值。这些发现表明,几个实验是验证和伪造Hodgkin和Huxley模型的测试。

We show that the action potential signals generated inside axons are reaction-diffusion solitons or reaction-diffusion waves, refuting the Hodgkin and Huxley hypothesis that action potentials propagate along axons with an elastic wave mechanism. Reaction-diffusion action potential wavefronts and solitons annihilate at collision and boundaries of axons, in contrast with elastic waves, where amplitudes add up and reflect at boundaries. We numerically calculate the values of the speed of the action potential spikes and the dispersion relations. These findings suggest several experiments as validating and falsifying tests for the Hodgkin and Huxley model.

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