论文标题
铁（III）结合的人体血清转铁蛋白的许多身体研究
Many body study of iron(III) bound human serum transferrin
论文作者
论文摘要
转铁蛋白是负责在所有脊椎动物中运输金属离子的蛋白质。然而，转铁蛋白的铁结合特性仍然鲜为人知。铁作为过渡金属，形成具有部分占领的3D子壳的离子。因此，结合铁蛋白的3D轨道内的电子被高度局部，并以复杂方式相互作用，无法通过分别考虑每个电子来完全表征。在这项工作中，我们利用动态平均场理论，该技术解释了这些电子之间的强烈相互作用。这是比研究转铁蛋白所用的更高的理论水平。我们提供了有关铁结合的人血清转移蛋白的有效自旋，多重态和光谱的新数据。
Transferrins are proteins responsible for transporting metal ions in all vertebrates. However, the iron binding properties of transferrins remain poorly understood. Iron, as a transition metal, forms ions with partially-occupied 3d subshells. The electrons within the 3d orbitals of iron-bound transferrin are therefore highly localized, and interact with one another in a complex manner that cannot be fully characterized by considering each electron separately. In this work, we make use of dynamical mean field theory, a technique that accounts for the strong interactions between these electrons. This is a higher level of theory than has ever been used to study transferrins. We present novel data on the effective spin, multiplet states and optical spectra of iron-bound human serum transferrin.
