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Quantum Information Networks (QINs) attract increasing interest, as they enable connecting quantum devices over long distances, thus greatly enhancing their intrinsic computing, sensing, and security capabilities. The core mechanism of a QIN is quantum state teleportation, consuming quantum entanglement, which can be seen in this context as a new kind of network resource. Here we identify use cases per activity sector, including key performance targets, as a reference for the network requirements. We then define a high-level architecture of a generic QIN, before focusing on the architecture of the Space segment, with the aim of identifying the main design drivers and critical elements. A survey of the state-of-the-art of these critical elements is presented, as are issues related to standardisation. Finally, we explain our roadmap to developing the first QINs and detail the already concluded first step, the design and numerical simulation of a Space-to-ground entanglement distribution demonstrator.