论文标题
基于超声检查的光学诊断和光疗治疗策略的方法
An ultrasonography-based approach for optical diagnostics and phototherapy treatment strategies
论文作者
论文摘要
目前，诊断医学使用从电离辐射到组织学分析的多种工具。随着压电晶体技术的进步，高频超声成像已经发展为实现相对较高的分辨率而没有电离辐射的缺点。这项研究提出了一种低成本，非侵入性和实时方案，用于使用超声成像为光疗程序提供信息。我们将当前可用的超声程序与蒙特卡洛方法相结合，用于评估组织中的光传输和光能沉积。高分辨率超声扫描的测量值用作光学模拟的输入。因此，这提供了一条管道，该管道将为医生提供更好的治疗策略计划。在验证通过生物组织的光传输的已知推断时，我们的结果突出了各种信息的范围，例如在不同深度处的时间监测和能量沉积。该过程还保留了测试各种波长的个体特定几何和解剖结构的灵活性。
Currently, diagnostic medicine uses a multitude of tools ranging from ionising radiation to histology analysis. With advances in piezoelectric crystal technology, high-frequency ultrasound imaging has developed to achieve comparatively high resolution without the drawbacks of ionising radiation. This research proposes a low-cost, non-invasive and real-time protocol for informing photo-therapy procedures using ultrasound imaging. We combine currently available ultrasound procedures with Monte Carlo methods for assessing light transport and photo-energy deposition in the tissue. The measurements from high-resolution ultrasound scans is used as input for optical simulations. Consequently, this provides a pipeline that will inform medical practitioners for better therapy strategy planning. While validating known inferences of light transport through biological tissue, our results highlight the range of information such as temporal monitoring and energy deposition at varying depths. This process also retains the flexibility of testing various wavelengths for individual-specific geometries and anatomy.
