论文标题

使用磁共振图像的基于深度学习的自动脑肿瘤分割的可行性研究

A Feasibility study for Deep learning based automated brain tumor segmentation using Magnetic Resonance Images

论文作者

Gunasekara, Shanaka Ramesh, Kaldera, HNTK, Dissanayake, Maheshi B.

论文摘要

深度学习算法已经解释了医学图像分析,解释和细分中人工智能研究的快速加速,并在医学中的各个子学科中进行了许多潜在的应用。但是,只有研究这些应用程序方案的数量有限的研究被部署到临床部门中,以评估实际需求和模型部署的实际挑战。在这项研究中,开发了基于深度卷积神经网络(CNN)的分类网络和更快的基于RCNN的定位网络,用于脑肿瘤MR图像分类和肿瘤定位。根据肿瘤定位的输出,将一种称为PreWitt的典型边缘检测算法用于肿瘤分割任务。使用目标质量参数,包括准确性,边界位移误差(BDE),骰子评分和置信区间,分析了所提出的肿瘤分割结构的总体性能。该模型的主观质量评估是根据双刺激损伤量表(DSIS)方案进行了使用医学专业知识的输入的。据观察,我们分割的产出的置信度与专家的范围相似。同样,神经科医生将模型的输出评为高度精确的分割。

Deep learning algorithms have accounted for the rapid acceleration of research in artificial intelligence in medical image analysis, interpretation, and segmentation with many potential applications across various sub disciplines in medicine. However, only limited number of research which investigates these application scenarios, are deployed into the clinical sector for the evaluation of the real requirement and the practical challenges of the model deployment. In this research, a deep convolutional neural network (CNN) based classification network and Faster RCNN based localization network were developed for brain tumor MR image classification and tumor localization. A typical edge detection algorithm called Prewitt was used for tumor segmentation task, based on the output of the tumor localization. Overall performance of the proposed tumor segmentation architecture, was analyzed using objective quality parameters including Accuracy, Boundary Displacement Error (BDE), Dice score and confidence interval. A subjective quality assessment of the model was conducted based on the Double Stimulus Impairment Scale (DSIS) protocol using the input of medical expertise. It was observed that the confidence level of our segmented output was in a similar range to that of experts. Also, the Neurologists have rated the output of our model as highly accurate segmentation.

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