论文标题

无模板制备热响应磁磁纤毛与生物条件兼容的

Template-Free Preparation of Thermoresponsive Mag-netic Cilia Compatible with Biological Conditions

论文作者

Grein-Iankovski, Aline, Graillot, Alain, Radiom, Milad, Loh, Watson, Berret, Jean-François

论文摘要

生物启发的材料通常用于功能设备的开发中。模仿生物学功能的人工纤毛的制造已成为微型化系统中流体操纵的有前途的策略。在这项研究中,我们提出了一种不同的物理化学见解,以制备基于温度触发的可逆氧化铁纳米颗粒在无生物兼容模板方法中的可逆装配。准备好的纤毛的长度可以在10到100微米之间调节,达到纵横比,在非常密集的柔性结构中,持久性长度约为8微米。纤毛的磁性致动揭示了稳健的结构(在数小时的驱动)中,由于细丝的敏感性高而产生了广泛的弯曲幅度。结果表明,提出的策略是模板制造方法的有效且通用的替代方法,并在无模板方法中产生具有显着特征和尺寸的纤毛。

Bio-inspired materials are commonly used in the development of functional devices. The fabrication of artificial cilia mimicking the biological functions has emerged as a promising strategy for fluid manipulation in miniaturized systems. In this study, we propose a different physicochemical insight for the preparation of magnetic cilia based on the temperature-triggered reversible assembly of coated iron oxide nanoparticles in a bio-compatible template-free approach. The length of the prepared cilia could be tuned between 10 and 100 microns reaching aspect ratios up to 100 in a very dense array of flexible structures with persistence lengths around 8 microns. Magnetic actuation of the cilia revealed robust structures (over several hours of actuation) with a wide range of bending amplitudes resulting from high susceptibility of the filaments. The results demonstrate that the proposed strategy is an efficient and versatile alternative for templated fabrication methods and producing cilia with remarkable characteristics and dimensions within the template-free approaches.

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