论文标题
朝着3D打印钻石的医疗植入物进展:评论
Progress towards 3D-printing diamond for medical implants: A review
论文作者
论文摘要
添加剂制造或3D打印用于在许多领域(例如国防,航空航天和医学)中创建定制物品。尽管在3D打印的骨科植入物中取得了进展,但在创建能够骨整合的材料的同时,在抑制植入物的细菌定殖的同时,仍然存在重大挑战。 Diamond迅速成为具有广泛生物医学应用的材料,尤其是由于其出色的生物相容性。但是,由于其极端的硬度和脆性,钻石是一种很难制造的材料。包括添加剂制造在内的新制造方法已经克服了其中的一些挑战,并引起了在软组织应用和硬组织应用中使用基于钻石的植入物的增加。因此,由于钻石的独特特性,它被认为是骨骼生长和随后的组织整合的促进者。这篇综述概述了为骨科应用制造钻石的最新进展,专门针对不同的制造方法及其在体外和体内的适用性。还讨论了在医疗植入技术中使用钻石的前景和挑战。
Additive manufacturing or 3D-printing is used to create bespoke items in many fields, such as defence, aerospace and medicine. Despite the progress made in 3D-printed orthopaedic implants, significant challenges remain in terms of creating a material capable of osseointegration while inhibiting bacterial colonisation of the implant. Diamond is rapidly emerging as a material with an extensive range of biomedical applications, especially due to its excellent biocompatibility. However, diamond is a difficult material to fabricate, owing to its extreme level of hardness and its brittleness. New methods of fabrication including additive manufacturing, have overcome some of these challenges and given rise to an increase in the use of diamond-based implants in both soft and hard tissue applications. Therefore, due to the unique properties of diamond, it is being considered as a facilitator of bone growth and subsequent tissue integration. This review outlines the recent progress in fabricating diamond for orthopaedic application, specifically focusing on the different fabrication approaches and their applicability in vitro and in vivo. The prospects and challenges for using diamond in medical implant technologies are also discussed.