论文标题
具有扩散MRI的微观结构:我们对什么尺度敏感?
Microstructure with Diffusion MRI: What Scale We Are Sensitive to?
论文作者
论文摘要
扩散加权MRI是旨在在体内评估细胞组织结构的迅速发展的微结构MRI的先驱。这篇简短的综述着重于使用不同扩散MRI技术访问的微观结构的时空尺度,并且需要将可测量性与结果的可解释性进行加权。扩散现象和模型首先在测量的二维空间(Q-T平面)中分类为狭窄的梯度脉冲。 Stejskal的三维参数空间 - Tanner扩散加权为该集合增加了更多现象。在扩散权重与目标细胞物种的几何形状相匹配的总体思想下,简要讨论了具有较大参数的现代测量技术。
Diffusion-weighted MRI is the forerunner of the rapidly developed microstructural MRI aimed at in vivo evaluation of the cellular tissue architecture. This brief review focuses on the spatiotemporal scales of the microstructure that are accessible using different diffusion MRI techniques and the need to weight the measurability against the interpretability of results. Diffusion phenomena and models are first classified in two-dimensional space (the q-t-plane) of the measurement with narrow gradient pulses. Three-dimensional parameter space of the Stejskal--Tanner diffusion weighting adds more phenomena to this collection. Modern measurement techniques with larger number of parameters are briefly discussed under the overarching idea of diffusion weighting matching the geometry of the targeted cell species.