论文标题

MSM中HIV传播的隶属网络模型

Affiliation network model of HIV transmission in MSM

论文作者

Larson, Jonathan, Onnela, Jukka-Pekka

论文摘要

在美国与男性发生性关系的黑人比白色MSM更可能是HIV阳性。在性伴侣会议场所,黑人与非黑色MSM的故意和无意间分离可能会使这一差异永存,这一事实被当前的HIV风险指数所忽略,这主要集中于个人行为而不是系统性因素。本文利用了最近的研究,其中MSM会见他们的性伴侣的场所。连接个人和场所会导致所谓的隶属网络;我们为艾滋病毒如何沿着这些网络传播的模型提出了一个模型,并根据此模型制定了一个新的风险指数。我们在芝加哥的466个非裔美国人MSM的隶属网络和模拟上测试了该新的风险指数。当有两组人(一个人比另一个人患HIV患病率高)时,新的风险指数效果很好,与他们的性伴侣相遇的重叠有限。

Black men who have sex with men (MSM) in the U.S. are more likely to be HIV-positive than White MSM. Intentional and unintentional segregation of Black from non-Black MSM in sex partner meeting places may perpetuate this disparity, a fact that is ignored by current HIV risk indices, which mainly focus on individual behaviors and not systemic factors. This paper capitalizes on recent studies in which the venues where MSM meet their sex partners are known. Connecting individuals and venues leads to so-called affiliation networks; we propose a model for how HIV might spread along these networks, and we formulate a new risk index based on this model. We test this new risk index on an affiliation network of 466 African-American MSM in Chicago, and in simulation. The new risk index works well when there are two groups of people, one with higher HIV prevalence than the other, with limited overlap in where they meet their sex partners.

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