论文标题
较低框架速率视网膜和脉络膜血流成像的反向对比激光多普勒全息图
Reverse contrast laser Doppler holography for lower frame rate retinal and choroidal blood flow imaging
论文作者
论文摘要
激光多普勒全息图(LDH)是一种基于多普勒光谱的全场测量值的干涉血流成像技术。到目前为止,LDH已在视网膜中使用超快摄像机(通常为75 kHz)证明。我们在这里表明,可以使用相机框架速率慢10倍,可以实现类似的方法。由于节能,低频和高频局部功率多普勒信号具有相反的变化,并且低频功率多普勒的简单对比反转显示,对于传统激光多普勒测量值的摄像机检测带宽超出了摄像机检测带宽。相关的血流变化和颜色复合功率多普勒图像可以通过摄像头速率降至几个kHz获得。
Laser Doppler holography (LDH) is an interferometric blood flow imaging technique based on full-field measurements of the Doppler spectrum. LDH has so far been demonstrated in the retina with ultrafast cameras, typically at 75 kHz. We show here that a similar method can be implemented with camera frame rates 10 times slower than before. Thanks to energy conservation, low and high frequency local power Doppler signals have opposite variations, and a simple contrast inversion of the low frequency power Doppler reveals fast blood flow beyond the camera detection bandwidth for conventional laser Doppler measurements. Relevant blood flow variations and color composite power Doppler images can be obtained with camera frame rates down to a few kHz.