论文标题
使用深度学习开发用于个性化电磁剂量法的精确人头模型
Development of accurate human head models for personalized electromagnetic dosimetry using deep learning
论文作者
论文摘要
从医学图像中的个性化人头模型的发展已成为电磁剂量测定领域的重要主题,包括优化电刺激,安全评估等。人头模型通常是通过将磁共振图像分割为不同解剖组织的。这个过程很耗时,需要特殊的经验来分割相对较大的组织。因此,精确计算不同特定大脑区域的电场是一项挑战。最近,深度学习已用于人脑的分割。但是,大多数研究仅集中在脑组织的分割上,并且很少对其他组织的关注,这对于电磁剂量测定非常重要。 在这项研究中,我们为卷积神经网络提出了一种新的架构,该卷积神经网络命名为knneket,以执行整个人头结构的分割,这对于评估大脑中的电场分布至关重要。提出的网络可用于生成个性化的头模型,并在经颅磁刺激期间应用于大脑中电场的评估。我们的计算结果表明,使用所提出的网络生成的头模型与通过手动分割在扫描仪内部分割任务中创建的网络表现出很强的匹配。
The development of personalized human head models from medical images has become an important topic in the electromagnetic dosimetry field, including the optimization of electrostimulation, safety assessments, etc. Human head models are commonly generated via the segmentation of magnetic resonance images into different anatomical tissues. This process is time consuming and requires special experience for segmenting a relatively large number of tissues. Thus, it is challenging to accurately compute the electric field in different specific brain regions. Recently, deep learning has been applied for the segmentation of the human brain. However, most studies have focused on the segmentation of brain tissue only and little attention has been paid to other tissues, which are considerably important for electromagnetic dosimetry. In this study, we propose a new architecture for a convolutional neural network, named ForkNet, to perform the segmentation of whole human head structures, which is essential for evaluating the electrical field distribution in the brain. The proposed network can be used to generate personalized head models and applied for the evaluation of the electric field in the brain during transcranial magnetic stimulation. Our computational results indicate that the head models generated using the proposed network exhibit strong matching with those created via manual segmentation in an intra-scanner segmentation task.